The gameplay of Worms Blast is similar to that of Puzzle Bobble/Bust-a-Move, but with several key differences. There is a hexagonal grid of coloured blocks at the top of the screen, while the player's character sits on a boat floating in water. Unlike Puzzle Bobble, it is able to move side to side. There are multiple weapons that can be used, however the only weapon the player has to start with is a bazooka. As with Worms, holding down the fire button increases the power behind the weapon's launch, affecting how far it will travel.