Baseline (Widescreen) Solution & Issues
Ultra/Super-Wide (21:9/32:9) Specific Solution & Issues
HUD is black beyond the 16:9 area (see screenshot).
Eyefinity / Surround Specific Solution & Issues
Multi-monitor resolutions are detected in-game but will crash the game (applies to both fullscreen and windowed mode).
The data files can be used with a source port such as EDuke32 to play at multi-monitor resolutions (some Megaton Edition features will not be available).
4k UHD Specific Solution & Issues