I don't know how well both Nv Surround and RFG handle vsync settings, but that's strange indeed.
Did you try DX9 mode (-nod3d10 command line parameter) ?
Good call. So when I force DX9 mode it appears to work as it should. So far I've just tried 7680 x 1600.
A few "issues" still though. For one, I think others are getting DX10 in 5040 x 1050 using NVS, so not sure why that won't work for me.
Also, when it loads forcing DX9, the intro menu is VERY sluggish (long delay between moving arrow key to select different things and movement on the screen). But least I can slowly get the game loaded. Once loaded it works fine.
Other issue is that so far I can't up any of the graphics settings at all. It seems anytime I change anything in the Display settings (from the main menu), that once I go into the game (even within the same session where I already started without the options file) it badly messes up.
So next I am going to try to see if I can edit any of the graphics settings from within a loaded game. I am also going to try and touch 1 setting at a time to see if just one of them is messing things up. I also am thinking of trying everything at some lower resolutions.
I still wish I had a better understanding of what is going wrong with DX10 because I am worried that I've done something wrong or different and this issue is going to crop up in other games that work for others.